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Mithu Guha
Division of Infectious Diseases and Immunology
Indian Institute of Chemical Biology
4, Raja S. C. Mullick Road
Jadavpur, Kolkata-700032
West Bengal, India
Email:
About Mithu
Research Interest
Mithu is from Hoogly district, West Bengal but she is born and brought up in Uttar Pradesh. She did her schooling from Kendriya Vidyalaya Gorakhpur. Then she completed her graduation from St. Andrew’s college, Gorakhpur in 2000. Mithu did her Master degree in biotechnology from Deen Dayal Upadhayay Gorakhpur University in 2002. Then she joined this group in April 2003 for carrying out her Ph.D research.
Mithu is currently working on oxidative stress mediated apoptosis of hepatocyte during malaria. She is trying to elucidate the pathway involved in the apoptosis of liver cells. Besides that Mithu is also working in cloning, overexpression and purification of some putative protein of plasmodium falciparum which can be used as drug target.
Publication
1. Mithu Guha, Sanjay Kumar, Vinay Choubey, Pallab Maity, Uday Bandyopadhyay. Apoptosis in the liver during malaria: Role of oxidative stress and implication of the mitochondrial pathway. FASEB J. 2006 (20) 1224-1226 2. Mithu Guha, Vinay Choubey, Pallab Maity, Sanjay Kumar, Kumkum Shrivastava, Sunil K Puri, Uday Bandyopadhyay. Overexpression, Purification and localization of apoptosis related protein from Plasmodium falciparum. Protein Expression and Purification. 2007 (52) 363-372 3. Mithu Guha, Pallab Maity, Vinay Choubey, Kalyan Mitra, Russel J Reiter, Uday Bandyopadhyay. Melatonin inhibits free radical-mediated mitochondrial-dependant hepatocyte apoptosis and liver damage induced during malarial infection. Journal of Pineal Research. 2007 (In Press). 4. Vinay Choubey, Mithu Guha, Pallab Maity, Sanjay Kumar, Resmi Raghunandan, Prakas R. Maulik, Umesh C. Halder, Uday Bandyopadhyay ‘Molecular characterization and localization of Plasmodium falciparum choline kinase’. Biochim Biophys Acta. general subjects 2006 (1760) 1027-1038. 5. Vinay Choubey, Pallab Maity, Mithu Guha, Sanjay Kumar, Uday Bandyopadhyay. Inhibition of Plasmodium falciparum Choline Kinase by Hexadecyltrimethylammonium Bromide: a Possible Antimalarial Mechanism. Antimicrobial agents and Chemotherapy. 2007 (51) 696-706. 6. Sanjay Kumar, Mithu Guha, Vinay Choubey, Pallab Maity, Uday Bandyopadhyay. Antimalarial drugs inhibiting hemozoin (ß hematin): a mechanistic update. Life science 2007 (80) 813-828.
Last updated: 25.09.2007
